If you’re looking to dominate other dwellers in Fallout 76’s PvP modes, having the right loadout is essential. Over the years, players have tested countless weapons to find out what really delivers in a fight—especially with the game’s evolving balance patches and Legendary Perks.

Below, I’ll share 17 tried-and-true weapons that can give you a major edge in Fallout 76 PvP. I’ll also sprinkle in a few tips for making sure you’re properly prepared, from farming to trading to those times when you just want to buy Fallout 76 Items to round out your build.

1. Bloodied Handmade Rifle

Classic for a reason. A Bloodied Legendary variant paired with damage boosts (Adrenaline, Bloody Mess) will melt other players if your health is low. It’s lightweight, customizable, and highly effective in VATS.

2. Anti-Armor Fixer

Probably the most popular PvP rifle. Fast fire rate, suppressed, and amazing hip-fire accuracy. The Anti-Armor effect cuts through tanky builds, making it a reliable dueling weapon.

3. Explosive Gatling Plasma

Post-nerf it’s not quite as OP as it used to be, but it’s still scary in PvP if you stack energy damage buffs. Great for chasing players in open terrain.

4. Quad Tesla Rifle

Not just for nuking events. The Quad Tesla can spam shots for days, which is great for keeping pressure on slippery players who like to run.

5. Junkie’s Lever Action Rifle

With chem stacking, this thing hits absurdly hard. If you can keep your addictions up, you’ll two-shot many lightly armored players.

6. Two Shot Gauss Rifle

The Gauss Rifle’s charged shots already do major damage, but Two Shot doubles the pain. Best for players with good aim and patience.

7. Anti-Armor 50 Cal Machine Gun

Reliable, big magazine, and punishes anyone relying on power armor. Best used with Heavy Gunner perks maxed out.

8. Quad Railway Rifle

Underrated, but devastating. Quad capacity removes its main drawback. The Railway Rifle’s spikes ignore armor and do massive limb damage.

9. Bloodied Gatling Gun

If you like tanking with power armor but want to keep Bloodied synergy, the Gatling Gun offers sustained DPS and good ammo economy.

10. Vampire’s Plasma Caster

A niche pick but extremely strong for duels. Heals you as you fight, letting you outlast opponents who rely on burst damage.

11. Two Shot Dragon

High-risk, high-reward. The Dragon deals huge damage if you land the shot. Not easy to use, but a game-ender in openers.

12. Instigating Gauss Shotgun

Perfect for ambushes. Double damage on first hit can one-shot many players, especially in VATS.

13. Anti-Armor Combat Shotgun

Excellent for CQC. Great fire rate and Anti-Armor ensures you’ll win most close-quarters scraps.

14. Explosive 10mm SMG

Solid hip-fire and spray potential. Explosive legendary effect adds reliable area damage and staggers.

15. Furious Power Fist

For melee builds. Stacking damage with each consecutive hit makes it brutal if you can close the gap.

16. Vampire’s Chainsaw (with Dual Bar Mod)

In melee duels, Vampire’s Chainsaw is absurdly tanky. You can trade hits fearlessly thanks to the life steal.

17. Quad Pump Action Shotgun

No reload worries. If you have good reflexes and VATS build synergy, you can clear multiple enemies quickly.

Tips for Getting These Weapons

Finding or rolling the perfect Legendary variant can take ages. Many players farm events like Radiation Rumble or Scorched Earth for drops, or trade with other players. But if you’re short on time, sometimes you might want to buy Fallout 76 Items from a trusted seller to complete your build.

Similarly, trading in-game often revolves around caps, and if you need to bulk up your wallet fast, some players choose to Buy Fallout 76 Caps online to make the process simpler.

Final Thoughts

PvP in Fallout 76 is a game of preparation and knowledge. Having one or two of these weapons in your stash can turn the tide in a fight, but knowing when and how to use them is just as important. Don’t be afraid to experiment, tweak your perk cards, and practice your aim.